乙型肝炎患者血清可溶性白细胞介素2受体测定的意义

The Significance of Detecting Serum Soluble Interleukin 2 Receptor for Hepatitis B Cases

[目的 ]检测乙肝患者血清可溶性白细胞介素 2受体 (sIL 2R )的水平及其与血清丙氨酸氨基转移酶 (ALT)、血清总胆红素 (SB)、白球蛋白比值 (A/G)、胆碱酯酶 (ChE)及乙肝病毒复制标志物之间的关系。 [方法 ]酶联免疫吸附试验 (ELISA)检测 66例乙肝患者和 2 0例健康对照组血清sIL 2R含量。[结果 ]乙肝患者血清sIL 2R水平高于对照组 ,其升高与ALT、SB、A/G和ChE相关 ,与乙肝病毒的存在和复制与否无关。[结论 ]急性、慢性、重型乙肝及乙肝后肝硬变患者血清sIL 2R水平 。

To detect the serum level of soluble interleukin 2 receptor (sIL 2R) and the relationships between sIL 2R and liver injury of hepatitis B patients (ALT, SB, A/G, ChE and antigen antibody system) \ The sIL 2R concentration was detected by ELISA method for 66 hepatitis B patients and 20 normal persons \ The level of SIL 2R of hepatitis B patients was higher than that in normal group and was correlated with ALT, SB, A/G and ChE significantly \ The serum levels of sIL 2R are increased significantly and related to the immune function, the degree of injury and inflammation in acute and chronic hepatitis B