摘要
Lung cancer is the leading cause of cancer deaths worldwide. Accurate early diagnosis is critical in increasing the 5-year survival rate of lung cancer, so the efficient and accurate detection of lung nodules,the potential precursors to lung cancer, is paramount. In this paper, a computer-aided lung nodule detection system using 3D deep convolutional neural networks(CNNs) is developed. The first multi-scale 11-layer 3D fully convolutional neural network(FCN) is used for screening all lung nodule candidates. Considering relative small sizes of lung nodules and limited memory, the input of the FCN consists of 3D image patches rather than of whole images. The candidates are further classified in the second CNN to get the final result. The proposed method achieves high performance in the LUNA16 challenge and demonstrates the effectiveness of using 3D deep CNNs for lung nodule detection.
Lung cancer is the leading cause of cancer deaths worldwide. Accurate early diagnosis is critical in increasing the 5-year survival rate of lung cancer, so the efficient and accurate detection of lung nodules,the potential precursors to lung cancer, is paramount. In this paper, a computer-aided lung nodule detection system using 3D deep convolutional neural networks(CNNs) is developed. The first multi-scale 11-layer 3D fully convolutional neural network(FCN) is used for screening all lung nodule candidates. Considering relative small sizes of lung nodules and limited memory, the input of the FCN consists of 3D image patches rather than of whole images. The candidates are further classified in the second CNN to get the final result. The proposed method achieves high performance in the LUNA16 challenge and demonstrates the effectiveness of using 3D deep CNNs for lung nodule detection.
作者
傅玲
马璟琛
陈奕志
LARSSON Rasmus
赵俊
FU Ling;MA Jingchen;CHEN Yizhi;LARSSON Rasmus;ZHAO Jun(School of Biomedical Engineering,Shanghai Jiao Tong University,Shanghai200240,China;SJTU-UIH Institute for Medical Imaging Technology,Shanghai Jiao Tong University,Shanghai200240,China;MED-X Research Institute,Shanghai Jiao Tong University,Shanghai200030,China;School of Technology and Health,KTH Royal Institute of Technology,SE-10044,Stockholm,Sweden)
基金
the National Natural Science Foundation of China(No.81371624)
the National Key Research and Development Program of China(No.2016YFC0104608)
the National Basic Research Program of China(No.2010CB834302)
the Shanghai Jiao Tong University Medical Engineering Cross Research Funds(Nos.YG2013MS30 and YG2014ZD05)
