慢性肾脏疾病患者冠脉病变特征及介入治疗

Characteristics of Coronary Artery Disease and Interventional Therapy in Patients with Chronic Renal Disease

本文旨在探讨慢性肾脏疾病患者的冠状动脉病变特征和经皮冠状动脉介入治疗(PCI)策略。并从CKD促进冠状动脉病变的机制、特点以及治疗策略三个方面予以综述。针对CKD患者冠状动脉病变复杂、血管钙化、扭曲严重、对PCI术者及手术器械要求更高等特点,术前需仔细评估手术风险,术中应建议选择犯罪血管进行干预,遵循救急救命的原则,术后的抗栓治疗需权衡获益和风险,合理选用药物及合适的用药剂量。

This paper aims to discuss the characteristics of coronary artery disease in patients with chronic kidney disease and the strategy of percutaneous coronary intervention(PCI). In this paper, three aspects on the mechanism,characteristics and treatment strategy of CKD to promote coronary artery disease are reviewed. According to the characteristics of CKD patients with complicated coronary artery disease, calcification of blood vessels, severe distortion, and higher requirements for PCI patients and surgical instruments, it's needed to carefully assess the operation risk before the surgery, the choice of blood vessel should be intervened during the operation,follow the principle of emergency life-saving, postoperative anti-thrombotic therapy should balance the benefits and risks, rationally select drugs and appropriate dosage.