糖尿病肾病防治新观点——美国第84届内分泌协会年会专题小结

New paradigms of managing diabetic nephropathy

糖尿病肾病是导致糖尿病死亡及终末期肾病透析的主要原因之一。在美国第 84届内分泌协会年会上报告了一些糖尿病肾病治疗新观点。内容包括 :HOPE研究结果 ;血管紧张素转换酶抑制剂 (ACEI)是糖尿病患者心血管甚至是肾功能不全的保护药 ;ACEI可能能够预防糖尿病 ;血管紧张素 1(AT1 )受体阻滞剂 (ARB)肾保护作用的证据 ;糖尿病中血压控制的重要性 ;ARB改善这些患者充血性心力衰竭及使用ACEI和ARB的临床建议等。

Diabetic nephropathy is a common cause to induce the death of diabetic patient and end stage renal disease and dialysis. At The 84th Annual Meeting of The Endocrine Society of America, several oral sessions were dedicated to the new paradigms of managing diabetic renal disease. They include antihypertensive drug classes, Results of HOPE clinical trial for diabetics, ACE Inhibitors may be cardioprotective for patients with diabetes, ACE inhibitors are cardioprotective even in renal funetion insufficient diabetic patients, ACE inhibitors may prevent diabetes, evidence of diabetic renal protection by ARBs, the importance of blood pressure control in diabetes and ARB benefits in congestive heart failure.