化学修饰酶在天然药物研究和生物技术中的应用

Chemical Dressing Enzyme:Its Application in Researches on Natural Drugs and Biotechnology

天然药物研究在现代药物开发中占有十分重要的地位 ,化学修饰可降低天然药物中酶蛋白的免疫原性 ,提高对热稳定性 ,延长酶在体内半衰期 ,提高药效 ;

Researches on natural drugs play a very important role in the development of modern medicines. Chemical dressing enzyme can reduces the immunogenicity of zymoprotein in natural drugs, improve stability against heat and prolong the half-life period of enzyme inside the body to improve efficacy of drugs. Meanwhile, chemical dressing enzyme has certain effects on the enzyme-controlled drug-releasing system in biotechnology and the confirmation of drug target site.