摘要
Objective:to research the antipyretic mechanisms of Buzhongyiqitang in reserpine induced splenasthenic rabbit.Method:The model of splenasthenic syndrome in rabbit was made by i.m.reserpine.Then,Buzhongyiqitang groups were given Buzhongyiqitang 5g/kg,10g/kg to stomach.On the 4 th day,observing the changes of temperature、PGE 2 in cerebrospinal fluid and cAMP in hypothalamus preoptic tissue between model group,control group and Buzhongyiqitang groups after i.v.TAB triple vaccine.Results:Buzhongyiqitang can remarkably reduce elevated temperature( P <0 01、 P <0 01),PGE 2 and cAMP.Conclusion:Buzhongyiqitang had antipyretic effect for reserpine induced splenasthenic syndrome with elevated temperature in rabbit.The mechanism is probably related to reducing PGE 2 and cAMP in concerned central nervous.
Objective:to research the antipyretic mechanisms of Buzhongyiqitang in reserpine induced splenasthenic rabbit.Method:The model of splenasthenic syndrome in rabbit was made by i.m.reserpine.Then,Buzhongyiqitang groups were given Buzhongyiqitang 5g/kg,10g/kg to stomach.On the 4 th day,observing the changes of temperature、PGE 2 in cerebrospinal fluid and cAMP in hypothalamus preoptic tissue between model group,control group and Buzhongyiqitang groups after i.v.TAB triple vaccine.Results:Buzhongyiqitang can remarkably reduce elevated temperature( P <0 01、 P <0 01),PGE 2 and cAMP.Conclusion:Buzhongyiqitang had antipyretic effect for reserpine induced splenasthenic syndrome with elevated temperature in rabbit.The mechanism is probably related to reducing PGE 2 and cAMP in concerned central nervous.
出处
《中国中医基础医学杂志》
CAS
CSCD
2003年第8期15-16,共2页
JOURNAL OF BASIC CHINESE MEDICINE
