电刺激对军人血浆褪黑激素昼夜节律的影响

The Effects of Electrostimulation upon Soldier's Circadian of Melatonin in Plasm

人体的生理与行为节律是由内源性昼夜节律钟产生与调控的。我们通过监测人体体核温度 ,就电针与光照肌对军人血浆褪黑激素节律的影响进行了研究 ,以探索电针调节人体节律的相位反应规律。实验结果显示 ,电针对军人血浆中的褪黑激素节律相位的影响具有明显的依时相性 ,其相位反应曲线呈光性模式。这一发现为治疗睡眠与节律混乱性疾病提供了新的思路。

Physiological and behavioral rhythms are governed by an endogenous circadian clock. In this paper are reported the studies on soldier's circadian of melatonin concentrations by means of electricity and light pulses presented to the popliteal region (behind the knee). The results showed that the phase of melatonin concentrations can be regulated by both the electricity pulses and the light pulses. A systematic relation was found between the timing of the electrostimulating and the magnitude and direction of phase shifts, resulting in the generation of a phase response curve. The phase response curve displayed photic model. These findings have implications for the development of more effective treatments for sleep and circadian rhythm disorders.