急性胰腺炎伴血清三酰甘油升高病人的临床特征分析

Clinical Features of Acute Pancreatitis Patients with Elevation of Serum Triglyceride Concentiation

目的:探讨急性胰腺炎(AP)伴有血清三酰甘油(TG)升高者的临床特点。方法:收集2000年1月至2002年1月期间本院外科99例AP,按入院时血清TG是否高于1.7mmol/L而将其分为TG升高组(28例和TG正常组71例)。结果:9例TG升高,占同期80例AP病人的11.3%。TG升高组在发病72h内,肺、心血管和肾脏功能障碍的发生率高于TG正常组(分别为25.0%比1.4%、17.9%比1.4%,和14.3%比1.4%,P<0.05),假性囊肿的发生率增高(53.6%比4.2%,P<0.05),有采用非手术治疗的趋势。结论:AP病人伴血清TG升高者的早期脏器功能障碍发生率增高,局部并发症率升高,常采用非手术治疗。

Objective:To evaluate the clinical characteristics of acute pancreatitis patients with elevation of serum triglyceride concentration.Methods:Ninety-nine cases of acute pancreatitis admitted from Jan2000to Jan2002were analyzed.Of these,28cases belonged to the triglyceride-elevated group and71cases to the triglyceride-normal group(serum trigly-ceride level>or<1.7mmol/L).Results:Acute pancreatitis patients with elevated serum triglyceride accounted for11.3%(9/80)of all acute pancreatitis cases in same period for this data.The occurrence of pulmonary,cardiovascular and renal dysfunction72hours within the onset of the disease were higher in the triglyceride-elevated group than in the group with normal triglyceride(25.0%vs1.4%,17.9%vs1.4%,14.3%vs1.4%,P<0.05).The incidence of pseudocyst was53.6%and4.2%respectively in the group with elevated triglyceride group and in the group with normal triglyceride(P<0.05).Con-clusions:In acute pancreatitis patients with elevation of serum triglyceride,organ dysfunction and local complications occurred commonly in early stage,and non-operative therapy was commonly adopted in the majority of these patients.