磁共振延迟增强显像诊断心肌梗死的临床研究

Assessment of myocardial infarction by magnetic resonance delayed enhancement imaging

目的 了解磁共振延迟增强(MR-DE)显像在心肌梗死诊断中的临床意义。方法 42例拟诊冠心病的患者,按临床分为心肌梗死、心肌缺血、正常3组,行MR-DE显像,其中25例行冠状动脉造影(CAG),并按冠脉狭窄程度分为狭窄<50％,50％～99％和100％3组。计算MR-DE检出心肌梗死的敏感性与特异性,并分别分析临床分组和CAG分组的MR-DE结果。结果 利用延迟增强判断心肌梗死,敏感性、特异性和诊断准确性分别为87.5％,94.1％和92.8％。出现延迟增强的比例,在临床分组中,分别为87.5％,8.7％和0％;在CAG分组中,分別为0％,50％和100％。结论 MR-DE显像对心肌梗死诊断有较高临床意义。

Objective To evaluate the clinical value of magnetic resonance - delayed enhancement(MR-DE) imaging in the assessment of myocardial infarction. Methods MR-DE imaging was used in 42 patients with suspected coronary artery disease. They were divided into three clinical groups: myocardial infarction(8) , myocardial ischemia(23), and normal(11). Twenty five of 42 patients underwent coronary angiography (CAG) and were divided into three CAG groups according to the extent of coronary stenosis<50% , 50-99% , and 100% . Results The sensitivity, specificity and diagnostic accuracy of MR-DE for detection of myocardial infarction were 87. 5% ,94. 1 % and 92. 8% , respectively. The proportion of delayed enhancement in the three clinical groups were 87. 5% , 8.7% and 0, respectively; and in the three CAG groups were 0, 50% and 100% , respectively. Conclusion MR-DE imaging has significant clinical value in detection of myocardial infarction.