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KF-Al_2O_3催化合成2-甲基-1-苄基苯并咪唑 被引量：3

Study of catalytical synthesis of 2-methyl-1-benzyl benzimdazole
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摘要 A new method of synthesis of 2 methyl 1 benzyl benzimidazole starting from 2 methyl benzimdazole and benzyl bromide was reported with KF Al 2O 3 as catlyst and DMF as solution.The influence of some reaction condition on yield was also tested,and the optimum conditions were obtained,the molecular ratio of catlyst and 2 methyl benzimdazole and benzyl bromide 1∶1∶1 05,the reaction temperature 20-25,and the yield 70 8%. A new method of synthesis of 2 methyl 1 benzyl benzimidazole starting from 2 methyl benzimdazole and benzyl bromide was reported with KF Al 2O 3 as catlyst and DMF as solution.The influence of some reaction condition on yield was also tested,and the optimum conditions were obtained,the molecular ratio of catlyst and 2 methyl benzimdazole and benzyl bromide 1∶1∶1 05,the reaction temperature 20-25,and the yield 70 8%.
作者 照那斯图 沃联群 吴卫平 周灯学 毛洁 朱兰芬 应亮 陈耀祥
机构地区 浙江医药高等专科学校 上海市卫生局卫生监督所
出处 《化学研究与应用》 CAS CSCD 北大核心 2003年第5期694-695,F003,共3页 Chemical Research and Application
关键词 KF—Al2O3 催化剂 催化合成 2-甲基-1-苄基苯并咪唑 KF-Al_2O_3 catlyst 2-methyl-1-benzyl benzimdazole synthesis
分类号 O626.23 [理学—有机化学] O643.36 [理学—物理化学]
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化学研究与应用
2003年 第5期

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