在安徽省新发现一种自然疫源性疾病——莱姆病

A Tick-borne Disease—Lyme Disease First Discovered in Anhui Province

采用间接免疫荧光技术,检测了采自安徽大别山区某县310份自然人群血清中的莱姆病IgG抗体。结果发观,确诊感染者(IgG抗体滴度≥1∶128)40人,确诊感染率12.9%;可疑感染者(IgG抗体滴度1∶64)29人,可疑感染率9.4%。在受检的48个自然村中,检出有感染者的自然村17个,占35.4%。而不同性别、不同年龄及职业的确诊感染率差异均无显著性。另外,还调查了本病不同病期常见临床表现的流行率以及具有临床表现患者血清中IgG抗体情况。本次研究首次证实安徽省是莱姆病疫源地,并初步探讨了本病的流行特征。研究结果提示本病的分布可能非常广泛,人群对本病普遍易感。这将为本病的进一步研究与防治提供重要线索和依据。

With indirect immunofluorescent assay technique(IFAT), 310 sera obtained from Dabie mountain areas were detected for IgG antibodies of borrelia burgdorferi. It was found that, 40 of these specimens had elevated levels of IgG antibodies(≥1: 128), & the confirmed infection rate was 12.9%. Similarly, 29 of them had elevated levels of IgG antibodies(1: 64), the doubtful infection rate was 9.4%. The confirmed infection rate did not different signifcantly among agegroups, sexes as well as occupations. Yet, the confirmed infection occured in up to 35.4% of natural villages surveyed (17/48). In addition, the IgG antibodies in sera of persons who had some common symptoms & signs of Lyme disease were also examined.By this Study, the foci of Lyme disease was firstly confirmed. in Anhui province. These preliminary findings showed that people were easily susceptible to borrelia burgdorferi, and the distribution of lyme disease may be very broad. These would give important cluse and basis to the further studies on Lyme disease.