桑椹的化学成分

Study on the chemical constituents of Mulberry

目的对桑科植物桑 (MorusalbaL .)的果实桑椹醇提取物中的化学成分进行提取分离和结构鉴定。方法色谱技术进行分离 ,MS、NMR和IR光谱解析及与对照品比较鉴定化合物。结果共分离得到 7个化合物 ,根据理化性质和谱学分析鉴定了其中的 5个化合物 ,分别为 3 ,4 丙叉基苯甲酸 (2 ,2 dimethyl 1 ,3 dioxa benzo[d]pentane 6 carboxylicacid,Ⅰ )、水杨酸 (salicylicacid ,Ⅱ )、琥珀酸 (succinicacid ,Ⅲ )、胡萝卜苷 (daucosterol,Ⅳ )和己六醇 (1 ,2 ,3 ,4,5 ,6 hexanehexanol,Ⅴ )。结论化合物Ⅰ、Ⅱ。

Objective To study the chemical constituents of the extract of Mulberry.Method The chemical constituents were isolated and purified by the various chromatographic methods such as sillica gel normal, pressurized column chromatography and preparative thin layer chromatography(PTLC), then the structures were identified by physicochemical properties and spectral analysis. Result Seven compounds were obtained and five of them were identified as 2,2-dimethyl-1,3-dioxa-benzo[d]pentane-6-carboxylic acid (Ⅰ), salicylic acid(Ⅱ), succinic acid(Ⅲ), β-daucosterol (Ⅳ), and 1,2,3,4,5,6-hexanehexanol (Ⅴ). Conclusion Among them, Ⅰ, Ⅱand Ⅴwere isolated from this genus for the first time.