血尿306例临床与病理分析

Clinical and pathological analysis of 306 children with hematuria

目的 研究血尿患儿的临床特征及肾脏病理特点。方法 对以血尿为首发及主要表现并具备肾活检病理诊断的 30 6例血尿患儿的临床与病理资料进行回顾性分析。结果 IgA肾病占 4 2 % ,系膜增殖性肾小球肾炎占 38% ,薄基底膜肾病占 6 % ,Alport综合征占 3% ,其他占 11%。 结论 血尿严重程度与病理类型无明显关系 ,伴大量蛋白尿或高血压者病理损害相对较严重。

Objective To investigate the clinical feature and renal pathological behavior in children with hematuria.Methods Retrospective analysis was performed in 306 children whose primary symptom was hematuria diagnosed by renal biopsy pathologically.Results Distributions of renal pathological type were:immunoglobulin A nephropathy 42 %,mesangial proliferative glomerulonephoritis 38 %,thin glomerular basement membrane nephropathy 6 %,Alport syndrome 3 %, others 11 %.Conclusions There was no significant relationship between the severity of hematuria and the renal pathological type.The relative severe pathological lesion was present in those with hematuria accompanying mass proteinuria and hypertension.