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Analysis of the T-Lymphocytes and Their Subpopu-lations of the Peripheral Blood in Patients with Urticaria 被引量:1

荨麻疹外周血T淋巴细胞及亚群的检测(英文)
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摘要 Objective: To study the function of cellular immunity of patients with urticaria.Methods:T-lymphocytes subpopulations of the peripheraal blood in 60 patients with urticaria and 40 henlthy controls were examined by flow cylonuetry. Results: The number of CD^3+ and CD^4+ cells in the urticaria group were significantly lower than those in the control group ( P<0. 01 ), especially in patients with acute urticaria. Conclusion: There was immunologic dysfunction of T lymphocyte in the patients with urticaria, and not only humoral immunity takes part but also cellular immunity plays a certain role in the pathogenesis of urticaria. Objective: To study the function of cellular immunity of patients with urticaria. Methods:T-lymphocytes subpopulations of the peripheral Mood ire 60 patients with urticaria and 40 healthy controls were examined by flaw cytometry. Results: The number of CD3+ and CD4+ cells in the urticaria, group were significantly lower than tliose in the control group (P<0. 01) , especially in patients with acute urticaria. Conclusion: There was immunologic dysfunction of T lymphocyte in the patients with urticaria, and not only humoral immunity takes part but also cellular immunity plays a certain role in the pathogenesis of urticaria.
出处 《Journal of Nanjing Medical University》 2003年第5期220-222,236,共4页 南京医科大学学报(英文版)
基金 Supported by Grant from Janssen Science Research Foundation(JS2001008)
关键词 T淋巴细胞 风疹 外周血 血细胞计数 urticaria T-lymphocyte subpopulation flow cytometry
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参考文献5

  • 1Elias Toubi,A. Adir-Shani,A. Kessel,Z. Shmuel,E. Sabo,H. Hacham.Immune Aberrations in B and T Lymphocytes Derived from Chronic Urticaria Patients[J].Journal of Clinical Immunology.2000(5)
  • 2Sakurai M,Oba M,Matsumoto K,et al.Acute infectious urticaria: clinical and laboratory analysis in nineteen patients[].Journal of Dermatology.2000
  • 3ZHANG Hong-ming,BI Zhi-gang.The effect of ultraviolet B radiation on the release of IL-6 in H_αC_αT cell line and the inhibitive effect of Famotidine[].Acta Universitatis Medicinalis Nanjing.2003
  • 4Piconi S,Trabattoni D,Iemoli E,et al.Immune profiles of patients with chronic idiopathic urticaria[].International Archives of Allergy and Immunology.2002
  • 5Irinyi B,Aleksza M,Antal-Szalmas P,et al.peripheral T lymphocytes in patients with chronic idiopathic urticaria[].Acta Dermato Venereologica.2002

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