期刊文献+

神经干细胞应用的理论基础和策略

The Theoretical Foundation and Strategies of the Neurostem Cell Application
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摘要 干细胞是指能自我更新和多向分化潜能的细胞,对各种变性病变和器官损害有潜在的治疗价值,目前已成为研究热点[1]。
出处 《医学研究通讯》 2003年第9期2-4,共3页 Bulletin of Medical Research
基金 科技部重大基础研究前期研究专项研究基金(课题批准号2002CCAO4400)
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参考文献8

  • 1Weissman IL. Stem cells: units of dvelopment,units of regeneration, and units in evolution.Cell, 2000, 100:157- 168.
  • 2Alvarez- Buylla A, Garcia- Verdugo JM. A unifled hypothesis on the lineage of neural stem cells. Bat Rev Neurosci, 2001, 2:287-293.
  • 3Jin K, Minami M, Lan JQ, et al. Neurogenesis in dentate subgranular zone and rostral subventrieular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci USA, 2001, 98(8) :4710-4715.
  • 4LaiK, Kaspar BK, Gage FH, Schaffer DV.Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat Neurosci,2003, 6 (1) :21-27.
  • 5Vescovi AL, Snyder EY. Establishment and properties of neural stem cell clones: plasticity in vitro and in vivo. Brain pathology, 1999, 9(3) :569- 598.
  • 6Artavanis TS, Band MD, et al. Notch signaling: cell fate control and signal integration in dvelopment. Science, 1999, 284:770- 776.
  • 7Villa A, Soy C. Establishment and properties of a growth factor- dependent.perpetual neural stem call line from the human CNS. Exp neurol,2001, 161 (1) :67-84.
  • 8gray JA, Grigoryan G. Conditional immortalized multipotential and multifunctional neural stem cell lines as an approach to clinical transplan-tayion. Cell Transplant , 2000, 9 (2) :153-168.

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