摘要
从中间体 4 - (4 -溴丁酰基 )苯基 -a ,a-二甲基乙氰开始 ,经缩合、还原、环化三步合成特非它唑 ,收率 11%。
Terfetrazole was prepared from new intermedium 4-(4-bromobutyryl)-phenyl- a,a-Dimethylacetonitrile by condensation,reduction and cyclization with an overall yield of 11%.
出处
《华西药学杂志》
CAS
CSCD
2003年第5期346-347,共2页
West China Journal of Pharmaceutical Sciences