抗菌药物使用的调查与管理

Investigation and management of antimicrobial agents usage

目的 了解某院抗菌药物使用情况及管理效果。方法 根据药剂科及检验科的原始登记数据进行汇总、统计 ,并从 1 998年 1月 1日～ 1 2月 31日及 2 0 0 0年 1月 1日～ 1 2月 31日的出院病历中 ,抽取住院号尾数为 0的病历 ,各科均抽满 4 0份为止 ,进行回顾性调查。结果 1 998年 1～ 1 2月耐药率比较高 ;抗菌药物总使用率为96 .2 5 % ,耗资比率为 5 2 .38% ;以治疗用药及二联用药为主。 2 0 0 0年 1～ 1 2月抗菌药物总使用率为 93.5 4 % ,耗资比率为 5 0 .4 7% ,以治疗用药及单用一种药为主。 2次调查的抗菌药物总使用率经过u检验 ,有显著性差异。结论 应对抗菌药物进行目标性管理 ,以减少抗菌药物滥用现象 。

Objective To evaluate the antimicrobial agents usage in a hospital. Methods Forty patients’ medical records were selected for retrospective analysis, patients were discharged in the year of 1998 and 2000 respectively. Results In 1998, antimicrobial resistant rate was higher, 96.25% of patients received antimicrobial agents, antimicrobial cost accounted for 52.38% of the total hospitalization expense; most antimicrobial agents were for treatment, the majority of patients received two kinds of antimicrobial agents simultaneously; in 2002, 93.54% of patients received antimicrobial agents, antimicrobial cost accounted for 50.47% , most antimicrobial agents were for treatment, and majority of patients only received one kind of antimicrobial drugs. There was significant difference in the total usage rate of antimicrobial agents between two surveys. Conclusion Target surveillance on antimicrobial agents usage should be carried out to reduce the overuse of antimicrobial agents and decrease the bacterial resistance.