30例感染性心内膜炎的临床分析

The clcnical analysis on 30 patients with infective endocarditis

目的:探讨感染性心内膜炎(IE)的病因,致病微生物的变迁及抗生素的选择。方法:对1995年5月～2003年8月间住院的30例IE患者的临床资料进行回顾性分析。结果:风湿性心脏瓣膜病为其主要的基础心脏病变。链球菌在致病微生物中依然居首位,但凝固酶阴性葡萄球菌(CNS)等其它菌种逐渐增多,且对青霉素耐药发生率高,为临床诊治造成困难。结论:对于IE患者应尽可能早期明确诊断,早期选用有效的抗生素。CNS在IE的致病微生物中的地位有待进一步提高。

Objective To investigate causes ,viciss itudes of pathogenic microorganisms and s election of antibi-otics in infective endocarditis(IE).Methods30patients with IE from May of 1995to August o f 2003were studied in retrospect.Results Rheumatic valvular heart disease i s the most important basically cadiac lesion.Streptococcus was the most common organism,but coa gulase negative staphylococcus(CNS)and other organisms were increased gradually.The resistants of Penicillin also increased.It made troubl e for clinical treatments.Conclusion It is rery important for IE patients to ma ke early diagnosis and select effective an tibiotics as soon as possible.CNS wi ll be more cared in microorganisms of IE.