890株伤寒、甲型副伤寒沙门菌耐药性分析

A Drug Resistance Detection to 890 Strains Typhoid or Paratyphoid Salmonella

目的 了解本省伤寒、甲型副伤寒沙门菌的耐药性 ,指导合理用药。方法 对各市 (地 )疾控中心提供的 890株伤寒、甲型副伤寒沙门菌株进行生化鉴定和血清学试验 ;药敏实验方法参照K B琼脂扩散法。结果 我省近几年来流行优势菌株甲型副伤寒沙门菌的耐药性明显高于伤寒沙门菌 ,不同地区及不同年份其耐药性均有一定差异 ,爆发型菌株的耐药性明显高于非爆发型菌株。结论 应根据不同菌型、地区及不同流行强度的伤寒、副伤寒做出相应防治措施。

Objective By a drug resistance detection to 890 strains typhoid or paratyphoid salmonella, to guide clinical medicine administration for typhoid or paratyphoid. Methods 890 strains typhoid or paratyphoid salmonella which were obtained from various cities or districts were carried out biochemical identification and serological test. And the drug resistance detection was referred to K-B agar diffusion method. Results In epidemic dominant strains for these years, the drug resistance of paratyphoid A salmonella was obviously stronger than that of typhoid salmonella. There were some differences in drug resistance among strains in different areas or different years. The drug resistance of epidemic strains was higher than that of non-epidemic strains. Conclusions Corresponding preventive measure should be taken out according to various strains, different area or diverse epidemic intension.