家兔实验性上颌窦炎窦口和窦腔黏膜的不同处理对纤毛运动功能的影响

The effect on cilia movement of experimental maxillary sinusitis in rabbits with different propose to ostia and mucosa

目的 :探讨家兔实验性上颌窦炎自然窦口和窦腔黏膜的不同处理对纤毛运动功能的影响。方法 :将已制成实验性上颌窦炎的 4 0只新西兰大白兔按术中黏膜处理不同以侧别分为 3组 :不处理黏膜组、部分切除黏膜组和全部切除黏膜组 ;按术中窦口处理不同分 2组 :窦口开放组和窦口扩大组。用活性碳粉末检测上颌窦黏液纤毛传输速度 (MCT) ,将测得的数据分别进行统计学处理。结果 :不处理黏膜组、部分切除黏膜组和完全切除黏膜组MCT检测结果分别为 4 .4 96± 1.0 2 1、3.892± 0 .92 5和 0 .80 9± 0 .14 7,3组间差异均有极显著性意义 (均P <0 .0 1) ;窦口扩大组 (4 .0 86± 1.0 4 2 )与窦口开放组 (3.995± 1.0 17)两组间差异无显著性意义 (P >0 .0 5 )。结论 :用活性碳检测上颌窦黏膜MCT是一种有效判断纤毛运动功能的方法 ;被切除的上颌窦黏膜术后虽会再生 ,但再生的黏膜纤毛运动功能较正常低下。

Objective:To investigate the effect on cilia movement of experimental maxillary sinusitis in rabbits with different dispose to ostia and mucosa.Method:Forty New Zealand White rabbits which had been induced experimental sinusitis were divided into 3 groups according to mucosa dispose during operation.The another two groups were divided accordin to different dispose ostia of maxillary sinus.Activated charcoal powder was used to test mucociliary transport (MCT) of maxillary sinus.Result:All data had be processed statistically.MCT of rabbits before operation were faster than that after operation and both of them were faster than the sinusitis group(P< 0.01).The difference of MCT in different propose of ostia groups was not significant(P> 0.05).Conclusion:It's a effective method to estimate the function of cilia using activated charcoal powder to test MCT of maxillary sinus.The function of regenerate mucosa after operation is lower than normal mucosa.The difference of MCT between ostia enlarged operation and ostia patent surgery is not significant.