HP感染与胃食管反流相关性分析(95例调查)

The Investigation of the Interelations between HP Infection and Gastroesophageal Reflux Disease(95 Attached Report)

目的:研究HP与GERD之间的关系。方法:观察95例经胃镜检查,确定为GERD的病人,分别①做血清抗体检测测定;②活检做快速尿素酶反应,两项阳性者确定HP(+),两项阴性者为(-)。观察GERD与HP两者之间的联系。结果:GERD阳性患者HP阳性率86.7％与阴性率13.3％有显著差异(X2=20.41 P<0.005),阴性患者HP阳性率42.9％与阴性率57.1％无显著差异。结论:HP相关性胃炎易导致GERD,且食管粘膜损伤较重。

Objective:To study the relations between HP and GERD.Methods:95 cases who were diagnosed as CERD by gastroscope were respectively given serum antibody checked and tested and one step diagnostic test for biopsy.Two positive items were determined as HP( + ) and two negative item as ( - ) .the relations between HP and GERD were observed.Results:To positive GERD patients,their HP positive rate was 86.7%,which was remarkably different from HP negative rate 13.3%(x2 = 20.41, P < 0.005).For negative GERD patients,their HP positive rate was 42.9% .which had no significant difference from their HP negative rate 57.1% .Conclusion: Gastritis related to HP was easily to cause GERD,and stomach mucosa is seriously damaged.