摘要
目的 :了解广州地区不动杆菌属的耐药情况 ,指导临床合理用药。方法 :对广州地区 12家医院1998年至 2 0 0 1年从临床分离的 4 36株不动杆菌属 ,严格按照 NCCL S规定的标准用纸片扩散法进行药敏试验。结果 :对 12种抗生素的耐药监测发现 ,不动杆菌属对亚胺培南、头孢哌酮 /舒巴坦、氨苄西林 /舒巴坦、替卡西林 /克拉维酸和哌拉西林 /三唑巴坦耐药率分别为 2 .8%、5 .6 %、14 .6 %、14 .6 %和 2 7.0 % ,对其他抗生素耐药率较高。结论 :本地区不动杆菌耐药现象较普遍 ,应引起临床高度重视。
Objective: To investigate the resistance of clinical Acinetobacter spp .isolates in Guangzhou district.Methods:436 strains of Acinetobacter spp .were isolated from 12 hospitals in Guangzhou area from 1998 to 2001 and the antibacterial susceptibility testing was performed by the disk diffusion method recommended by the National Committee for Clinical Laboratory Standards(NCCLS).Results: By determining the drug susceptibility of Acinetobacter spp . to 12 antibiotics,it was found that the resistant rates of bacterium to imipenem,cefoperazone/sulbactam,ampicillin/sulbactam,ticarcillin/clavulanic acid piperacillin/tazobactam were 2.8%,5.6%,14.6%,14.6% and 27.0%,respectively.The resistant rates to other antibiotics were also high.Conclusions: Acinetobacter spp . has high rate of resistance to antibacterial agents in Guangzhou.
出处
《中国微生态学杂志》
CAS
CSCD
2003年第5期270-271,共2页
Chinese Journal of Microecology
基金
广州市科技重点攻关项目 (2 0 0 0 -Z-0 2 7-0 1-2 -2 )
