前列腺癌基因治疗进展

Advances on Gene Therapy for Prostatic Cancer

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摘要前列腺癌(Prostate cancer，Pca)是男性泌尿生殖系统最常见的肿瘤，根据美国癌症协会的最新统计资料：在美国，2003年预计将有220 900新发现的前列腺癌病例，估计将有28 900人死于前列腺癌。

作者孙颖浩

机构地区第一军医大学长海医院

出处《医学研究通讯》 2003年第10期5-8,共4页 Bulletin of Medical Research

关键词前列腺癌基因治疗男性泌尿生殖系统肿瘤腺病毒载体逆转录病毒

参考文献8

1Greenlee RT.et al.Cancer statistics 2000.CA Cancer J Clin,2000. 50 (1) :7-33.
2Morris MJ.et al.Novel strategies and therapeutics for the treatment of the prostate carcinoma.Cancer, 2000, 89 (6) :1329-1348.
3Shalev M.et al.Gene therapy for prostate cancer,Urology, 2001, 57 (1) :8-16.
4Li S, Huang L.Nonvirul gene therapy: promises and challenges. Gene Ther, 2000, 7 (1) :31-34.
5Paielli DL.et al.Evaluation of the biodistribution,persistence,toxicity,and potential of germ-line transmission of a replication-competent human adenovirus following intraprostatic administration in the mouse,Mol Ther 2000, 1(3) :263- 274.
6Miyake H.et al.Chemosenaitization and delayed androgen-independed recurence of prostate cancer with the use of antisence Bcl-2 oligodeoxynucleotides.J Natl Cancer Inst, 2000,92 (1) :34-41.
7Nurris JS et al. Design and testing of ribozymes for cancer gene therapy.Adv Exp Med Biol, 2000, 465:293-301.
8Teh BS.et al.Phase Ⅰ/Ⅱtral evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostete cancer-a preliminary report.Int J Radiat Oncol Biol Phys, 2001, 51 (3) :605-613.

医学研究通讯

2003年第10期

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