低胆红素血症与冠心病

Low Bilirubinermia and Coronary Heart Disease (CHD)

目的 探讨低胆红素血症与冠心病的关系。方法 采用酶法对95例冠心病患者的血清总胆红素(TBIL)、高密度脂蛋白胆固醇(HDL-C)、胆固醇(TC)和甘油三酯(TG)进行测定。结果 冠心病患者中低总胆红素者82例(≥416μmol/L)占86.3％,与健康对照组血总胆红素浓度存在显著差异(P<0.01),同时在冠心病组中,对总胆红素与HDL-C、TC、TG进行的相关分析结果显示T-BIL与其它三项无显著相关性(P>0.05)。结论 低胆红素血症与冠心病间存在着密切关系,是独立于血脂之外的冠心病危险因素。

Objective To study the relations between decrease of serum total bilirubin and CHD. Method Serum total bilirubin, HDL-C,TC and TG were deteminded in 95 patients with CHD by using enzymatic method. Result 82 patients with low value of total bilirubin in the patients with CHD (≥416 μmol/L),the percentage was 86. 3%(82/95). There was significant difference of total bilirubin between these patients with CHD and normal control(P<0. 01). There was no relation between T-BIL and any of HDL-C,TC or TG(P>0. 05) in the patients with CHD. Conclusion Independent to blood lipids,low T-BIL concentration is related to CHD and is one of risk factors.