98例脑垂体瘤患者肺功能分析

The analysis of the pulmonary function of pre-operative patients with cerebral tumor

目的 探讨脑垂体瘤对肺功能的影响。方法 病例选择为 2 0 0 1年 7月～ 2 0 0 2年 6月临床诊断为脑垂体瘤并拟行脑垂体瘤切除术的患者 98例 (男 4 2例 ,女 5 6例 ) ,平均年龄 4 8.5± 1.4岁。所有患者在手术前后进行肺功能检查。结果 98例脑垂体瘤患者术前FEV1异常率 6 0 % ,术后异常率 2 2 % ,正常对照组异常 19% ;FEV1/Vcmax %术前异常率 18% ,术后异常率 12 % ,正常对照组异常 13% ;MVV术前异常率 78% ,术后异常率2 4 % ,正常对照组异常 15 % ;PEF术前异常率 79% ,术后异常率 19% ,正常对照组异常率 15 %。结论 脑垂体瘤患者术前EFV1降低 ,FEV1/Vcmax正常 ,MVV ,PEF降低 ,说明有限制性通气障碍 ,FEV1术后恢复与正常对照组无显著性差异。

Objective To discuss the cerebral tumor effect to the respiratory function.Methods We enrolled ninety eight patients with cerebral tumor,42 males and 56 females with average age of 48.5±1.4,who had been clinically diagnosed cerebral tumor and been waiting for operation,and a hundred and one normal been controled,50 males and 51 females with average age of 47.5±1.5,from July 2001 to June 2002.All enrolled samples received respiratory function examinations,including FEV1,FEV1/Vcmax%,MVV,PEF.Results The abnormality of FEV1,FEV1/Vcmax%,MVV,PEF were 60%,18%,78%,79%,respectively in the tumor group and those in the control were respectively 19%,13%,15%,15%.Those parameters,including FEV1,MVV,PEF,reduced compared with those in control,except to FEV1/Vcmax%.These reduces had statistically significant differences.Conclusions All the parameters we used in this trial are commonly used to show the pulmonary ventilatory function before the operation.We found the FEV1,MVV,PEF of the patients with cerebral tumor were significant lower than normal.We thought the restrictive ventilation disorders were likely the concomitant of the patients with cerebral tumor.