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广东汉族人β_2-肾上腺素能受体基因Gln27Glu多态性 被引量：2

Genetic Polymorphism of β_2-AR Gln27Glu in the Han of Guangdong
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摘要 目的　探讨 β2 -AR 16位点基因多态性在广东汉族人群中的分布 .方法　应用聚合酶链反应技术对 12 2例正常人 β2 -肾上腺素能受体基因Gln2 7Glu进行扩增并进行图谱分析 .并结合文献进行了不同种族间的分析比较 .结果　广东汉族人群 β2 -AR基因 2 7位点多态性分布频率 :Gln/Gln基因型占 36 .88% ,Gln/Glu基因型占 5 2 .4 6 % ,Glu/Glu基因型占 10 .6 6 % .结论　广东汉族人群存在出 β2 -ARGln2 7Glu基因多态性 ,其分布频率与英美高加索人群有一定差异 . Objective To identify the distribution feature of β 2-ARGln27Glu gene in the Hans in Guangdong Province. Methods β 2-ARGln27Glu genes from normal individuals were amplified with PCR. Results It was shown that the gene frequency of β 2-AR Gln27Glu was as followed;genotypefrequency:Gln/Gln 36.88%,Gln/Glu 52.46%,Glu/Glu 10.66%. Conclusions β 2-AR Gln27Glu gene s distribution in the Hans in Guangdong Province is different from those in other areas.
作者 何美玲 饶卫农 陈盛强
机构地区 广州市中医院 广州医学院
出处 《现代临床医学生物工程学杂志》 2003年第5期413-414,417,共3页 Journal of Modern Clinical Medical Bioengineering
关键词 广东 汉族人 Β2-肾上腺素能受体 基因多态性 GLN27GLU Guangdong Han population β 2-AR Gln27Glu Polymorphism
分类号 R346 [医药卫生—基础医学]
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参考文献9

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共引文献16

同被引文献51

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二级引证文献15

现代临床医学生物工程学杂志
2003年 第5期

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