水合氯醛不同给药途径用于眼科患儿制动效果探讨

Anesthetic Effects of Chloral Hydrate Given by Different Routes in Children before Ophthalmic Examination

目的探讨眼科检查前不同年龄患儿对 10 %水合氯醛不同用药途径制动效果。方法对 4 6 5例眼科检查患儿 ,按年龄分为婴儿 (15 1例 )、幼儿 (15 6 )例、学龄前 (15 8例 )共 3组 ;随机予口服 (2 36例 )或灌肠 (2 2 9例 )途径给药。结果制动效果 ,婴儿组口服给药明显优于灌肠法给药 (P <0 .0 1) ;幼儿及学龄前组灌肠给药法明显优于口服给药法 (P <0 .0 1)。结论应用 10 %水合氯醛制动 ,婴儿宜选用口服 ,幼儿及学龄前患儿宜选用灌肠法给药。

Objective To investigate the anesthetic effects of 10 % chloral hydrate given by different routes in children with different ages before ophthalmic examination. Methods Before ophthalmic examinations 465 children were divided into three groups: infants (151 cases), little children (156 cases), and children before school age (158 cases). Then they were randomly divided into oral group (236 cases) and clysis group (229 cases). Results The anesthetic effects of oral routes were significantly better than those of clysis routes in the group of infants ( P< 0.01), while those of clysis routes were better than those of oral routes in the group of little children and children before school age ( P< 0.01). Conclusion It is more satisfactory to give 10 % chloral hydrate orally in infants and by clysis in little children and children before school age.