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阿卡波糖对糖耐量低减患者胰岛细胞功能和胰岛素敏感性的影响

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摘要 目的 探讨阿卡波糖对糖耐量低减 (IGT)患者胰岛细胞功能和胰岛素敏感性的影响。方法  5 0例确诊IGT患者随机平分为阿卡波糖干预治疗的观察组和单纯生活方式控制的对照组。观察患者反映机体胰岛素抵抗程度的HOMA -IR指数和反映胰岛细胞功能的胰岛早期分泌功能指数 (ESSI)的变化。结果 与单纯生活方式干预的对照组相比 ,观察组服用阿卡波糖 3个月后 ,餐后血糖、空腹和餐后 2h血清胰岛素、C肽、血清甘油三酯、HOMA -IR指数和ESSI指数明显低于前者。与服用阿卡波糖前相比 ,观察组的上述指标也有明显降低。
出处 《广东医学》 CAS CSCD 2003年第11期1217-1219,共3页 Guangdong Medical Journal
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