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骨髓间充质干细胞在骨组织工程中的应用

Application of Bone Marrow Mesenchymal Stem Cells in Bone Tissue Engineering
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摘要 间充质干细胞可以分化为成骨细胞、成纤维细胞、神经细胞等多种组织细胞。研究者从骨髓中分离提取骨髓间充质干细胞 ,并通过诱导和体外培养使之分化为成骨细胞 ,作为骨组织工程的种子细胞。 Mesenchymal Stem Cells(MSCs) have the potential to differentiate into lineages of tissue cells,such as osteoblast,fibroblast,nerve cell et al.The researchers separated Mesenchymal Stem Cells from the marrow and induced MSCs to differentiate into osteoblast and these osteoblasts are served as seeding-cell of bone tissue engineering.
作者 杨立华 王远亮 何创龙 潘君
机构地区 重庆大学生物工程学院生物力学及组织工程教育部重点实验室
出处 《生物医学工程研究》 2003年第3期59-61,共3页 Journal Of Biomedical Engineering Research
基金 国家自然科学基金 (30 2 70 395 19872 0 80 ) 教育部基金资助项目
关键词 骨髓间充质干细胞 种子细胞 组织工程 诱导 分化 Mesenchymal stem cells Seeding-cells Tissue engineering Induction Differentiation
分类号 R68 [医药卫生—骨科学] R318 [医药卫生—生物医学工程]
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参考文献13

  • 1卢晓风,李胜富,程惊秋.骨髓间充质干细胞及其在骨/软骨缺损修复中的应用进展[J].生物医学工程学杂志,2002,19(1):135-139. 被引量：8
  • 2[2]Herve Petite,Veronique Viateau,Wassila Bansaid et al.Laboratoire de recherches orthopediques,CNRS UPRES A 7502.Universite D.Diderot,Faculte de Medccine Lariboisiere Saint-Louis,10 avenue de Verdun,2000.
  • 3舒胜文,李盛琳,马绪臣.骨髓间充质干细胞[J].现代口腔医学杂志,2002,16(1):84-86. 被引量：1
  • 4[4]Jay G.Shake MD,Peter J. Gruber MD,PhD et al.Mesenchymal stem cell impoangtation in a swine myocardial infarct model:engraftment and functioncal effects.Presented at the Thirty-seventh Annual Meeting of The Society of Thoracic Surgeons. New Orleans:LA,2001.Jan,29～31.
  • 5[5]Douglas R.Martin,Nancy R.Cox,et al,Isolation and characterization of multipotential mesenchymal stem cells from feline bone marrow.Experimental Hematology,2002,30(8):879～886.
  • 6李秀森,郭子宽,杨靖清,刘晓丹,侯春梅,唐佩弦,毛宁.骨髓间充质干细胞的生物学特性[J].解放军医学杂志,2000,25(5):346-348. 被引量：50
  • 7[7]Raimund strehl,Ph.D.,Karl schumacher,M.D.,Uwe de vires,M.S.et al,Proliferating cells versus differentiated cells intissue engineering.Tissue Engineering,2002,8:1.
  • 8[8]M.Wiedmann-AL-Ahmad,R.Gutwald,G.Lauer et al.How to optimize seeding and culturing of human osteoblast-like cells on various biomaterials.Biomaterials,2002,23:3319～3328.
  • 9[9]Dietmar W.Hutmacher.Scaffold design and fabrication technologies for engineering tissue-state of the art and future perspectives.J.Biomater.Sci.Polymer Edn,2001,12(1):107～124.
  • 10[10]D.Green.D.Walsh,S.Mann,and R.O.C.OREFFO.The potential of biomimesis in bone tissue engineering:lessons from the design and synthesis of invertebrate skeletons.Bone,2002,30(6):810～815.

二级参考文献69

  • 11，Prockop D J. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science， 1997，276:71
  • 22，Pittenger MF, Mackay AM, Beck SC et al. Multilineage potentiall of adult human mesenchyma stem cells. Science,1999,284: 143
  • 33，Ferrari G, Cusellade Angelis G, Coletta M et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science,1998, 279:1528
  • 44，Dexter TM, Allen TD, and Lajtha LG. Conditions controlling the proliferation of hematopoietic stem cells in vitro. J Cell Physiol,1977, 91: 335
  • 55，Bruder SP, Ricalton NS, Boynton RE et al. Mesenchyma stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiation. J Bone Miner Res,1998,13:655
  • 66，Conget PA, Minguell JJ. Phenotypical and functional properties of human bone marrow mesenchyma progenitor cells. J Cell Physiol,1999, 181: 67
  • 77，Fleming JE Jr, Haynesworth SE, Cassiede P et al. Monoclonal antibody against adult marrow-derived mesenchyma stem cells recognizes developing vasculature in embryonic human skin. Dev Dyn,1998,212:119
  • 8[1]Dexter T,Shadduck R.The regulation of haemopoiesis in long term bone marrow cultures: Role of L-cell CSF.J Cell Phys,1980, 102: 279-286.
  • 9[2]John J.Differentiation factors induce expression of muscle, fat cartilage, and bone in a clone of mouse pluripotent mesenchymal stem cells. The Ame. Surg,1995, 61:231-235.
  • 10[3]Latjha LG.haematopoietic stem cells: concepts and definitions. Blood cells, 1979, 5: 447.

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生物医学工程研究
2003年 第3期

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