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遗传性抗凝因子缺陷症的基因诊断 被引量：2

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摘要 正常人体凝血和抗凝血的平衡是维持凝血生理状态的重要机制,抗凝因子基因缺陷会导致相应的血栓性疾病.本文就遗传性抗凝因子(抗凝血酶、蛋白C、蛋白S和因子Ⅴ Leiden突变)缺陷症,结合我们的研究结果作一简述.
作者 王鸿利 王学锋
机构地区 上海第二医科大学附属瑞金医院
出处 《血栓与止血学》 2003年第4期173-175,共3页 Chinese Journal of Thrombosis and Hemostasis
关键词 遗传性抗凝因子缺陷症 基因诊断 遗传性蛋白C缺陷症 遗传性蛋白S缺陷症 遗传性凝血因子V LEIDEN突变
分类号 R554 [医药卫生—血液循环系统疾病] R394 [医药卫生—医学遗传学]
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二级参考文献13

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共引文献42

同被引文献15

  • 1周荣富,王鸿利.遗传性蛋白C缺陷症的研究进展[J].国外医学（输血及血液学分册）,2005,28(3):227-230. 被引量：9
  • 2张付华,吴竞生.遗传性抗凝血酶缺乏症研究进展[J].血栓与止血学,2005,11(6):284-286. 被引量：4
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  • 4[4]SHEN MC,LIN JS,TSAY W.High prewalence of antithrombin Ⅲ,protein C and protein Sdeficiency,but no factor Ⅴ Leiden mutation in venous thrombophilie Chinese patiences in Taiwan [J].Throm Res,2000,88:377-379.
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  • 7Liang Tang,Xiao‐Rong Jian,Naotaka Hamasaki,Tao Guo,Hua‐Fang Wang,Xuan Lu,Qing‐Yun Wang,Yu Hu.Molecular basis of protein S deficiency in China[J]. Am. J. Hematol. . 2013 (10)
  • 8Haoyu Deng,Jiaquan Chen,Hui Xie,Yi Gu,Kai Yuan,Peng Wang,Wei Shen,Wei Liang,Hao Zhang,Jiwei Zhang,Jun Xie,Lan Zhang.Rare double heterozygous mutations in antithrombin underlie hereditary thrombophilia in a Chinese family[J]. Journal of Thrombosis and Thrombolysis . 2013 (3)
  • 9Paolo Bucciarelli,Valerio De Stefano,Serena M. Passamonti,Daniela Tormene,Cristina Legnani,Elena Rossi,Giancarlo Castaman,Paolo Simioni,Michela Cini,Ida Martinelli.Influence of proband’s characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms[J]. Blood . 2013 (15)
  • 10Liang Tang,Hua-Fang Wang,Xuan Lu,Xiao-Rong Jian,Bi Jin,Hong Zheng,Yi-Qing Li,Qing-Yun Wang,Tang-Chun Wu,Huan Guo,Hui Liu,Tao Guo,Jian-Ming Yu,Rui Yang,Yan Yang,Yu Hu.Common genetic risk factors for venous thrombosis in the Chinese population[J]. The American Journal of Human Genetics . 2013

引证文献2

二级引证文献4

血栓与止血学
2003年 第4期

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