肝硬化的临床流行病学分析

Clinico-Epidemiological Analysis on Liver Cirrhosis

采用x、x2 及P值统计学方法观察一组大样本肝硬化住院病例的主要临床流行病学指标。结果显示临床发病构成比为 1 39% ,占全部肝病住院病例之 5 1 0 7%。病死率为 11 79%。病因学分析表明 88%病例与HBV感染相关 ,主要HBV标记组合形式为HBsAg +抗HBe +抗HBc及HBsAg +抗HBc ,单项抗HBc及并抗HBe和 (或 )抗HBs者亦非少数。直接死因以上消化道出血为最主要 (80 42 % ) ,伴脑病肝衰竭次之。由于肝硬化以与HBV相关者为最多 ,故其预防当从防治乙型肝炎入手。

WT5”BZ]Observe the main clinico epidemiological index of a large group of samples(8,016 in patient cases)of liver cirrhosis Adopting the statistical method of x,x 2 and Pvalue the proportion of clinical onset of liver cirrhosis is 1 39%,and accounting for 51 07% of all the in patients suffering from liver diseases and the case fatality rate is 11 79% Etiological analysis confirmed that 88 00% cases are correlative with HBV infection The main HBV marker pattern are“HBsAg+anti HBe+anti HBc”(40 79%)and“HBsAg+anti HBc”(28 71%),but single anti HBc and double anti HBe and/or anti HBs are not less as imagined For direct death causes,hemorrhage of digestive tract(80 42%)is the most common cause and the second is hepatic failure complicated with hepatoencephalopathy Most cirrhoses is correlative with HBV The aim of the study is to evaluate the effects for 88% of all the sampled liver cirrhoses cases Therefore to decrease the death rate of cir rhoses pveveutian and care for hepatitis B are important