免疫增强剂对反复呼吸道感染患儿免疫指标的影响

EFFECT OF IMMUNOPOTENTIATORS ON THE IMMUNE INDICES IN CHILDREN WITH RECURRENT RESPIRATORY TRACT INFECTION

目的 观察免疫增强剂对反复呼吸道感染 (RRTI)患儿免疫指标的影响。方法 :用琼脂单向扩散法和荧光法 ,检测了 10 0例RRTI患儿分别用乌体林斯注射液和转移因子口服液治疗前后免疫球蛋白含量和T细胞亚群百分数 ,并与正常对照组比较。结果 :RRTI组患儿免疫指标均非常显著低于正常对照组 (P <0 .0 0 1) ,乌体林斯注射液含服治疗后IgG .IgM含量和CD3、CD4 、CD8百分数均有显著升高 (P <0 .0 5 ) ;转移因子口服液口服治疗后IgA .IgM含量和CD3、CD4 百分数均有显著升高 (P <0 .0 5 )。结论 免疫功能降低是RRTI发病的重要因素 ,免疫增强剂对RRTI疗效佳。

Objective: To observe the effects of immuno-potantiators on the immune indices in children with Recurrent Respiratory Tract Infection(RRTI).Methods:Levels of Immune golbufins(IgG.IgM.IgA)and percentages of T cell subgroups(CD 3.CD 4.CD 8)were measused in 100 cases of children with RRTI before and after treating with Utilin“s”Injetction and Transfer Factor Oral Fluid,then compared with those in the control group.Results:In RRTI groups,the levels of immune indices were lower than those of the control groups very respectively(P<0.001).As campared with before treatment,the levels of IgG.IgM and the percentages of CD 3.CD 4.CD 8 were obviously increased after treatment of Utilin“s” Injetction given by sublingually;the levels of IgA.IgM and the percentages of CD 3.CD 4 were obviously increased after treatment of Transfer Factor Oral Fluid given by mouth.Conclusion:The hypoimmunofunction is an important factor in RRTI pathogenesis,and immunopotentiators produce good curative effects on treating RRTI.