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去甲万古霉素治疗耐甲氧西林葡萄球菌属感染的评价

Evaluation of Norvancomycin in Treatment of MRS Infections
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摘要 评价去甲万古霉素治疗耐甲氧西林葡萄球菌属感染疗效。方法:用国产去甲万古霉素(万迅)治疗耐甲氧西林葡萄球菌院内感染的病人34例,每d总量1.2g,治疗平均10.2d,观察其症状、体征变化及细菌清除情况。结果:治愈29例,好转4例,无效1例,总有效率98.3%。临床未见肝肾功能损害,治疗后细菌的总清除率为85.3%。结论:国产去甲万古霉素治疗耐甲氧西林葡萄球菌属感染临床效果满意,且经济、安全。 OBJECTIVE: To evaluate the therapeutic effect of norvancomycin in treating MRS infections. METHODS: 34 cases of nosocomial MRS infections were treated with domestic norvancomycin at a dose of 1. 2g/d with an average therapeutic course of 10.2d.The changes of symptoms and signs as well as bacterial clearance were observed. RESULTS: Among the 34 cases, 29 were cured, 4 improved and one was unsatisfactory, a total effective rate being 98. 3%. No liver and kidney dysfunctions were found. The total bacterial clearance rate was 85. 3%. CONCLUSION; The domestic norvancomycin is effective, inexpensive and safe in treating MRS infections.
出处 《中国医院用药评价与分析》 2001年第1期21-22,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 去甲万古霉素 药物治疗 耐甲氧西林葡萄球菌属感染 副作用 norvancomycin MRS therapy evaluation
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