11522张门诊处方中抗菌药物应用情况调查

Investigation in the Use of Antimicrobials in 11 522 Prescriptions for Outpatients of Our Hospital

目的:指导临床合理应用抗菌药物。方法:随机抽取我院门诊西药房1999年3月～5月的处方11 522张,对应用的抗菌药物的品种、出现频率、给药途径及联合用药等情况进行统计分析。结果:抗菌药物应用率为39.11％,应用品种有58种,主要是青霉素类、喹诺酮类、氨基糖苷类;以单种药物治疗为主(75.30％),2种联用占21.86％,最多可达4种联用(0.84％);用药途径以口服为主;疗程最长为60d。结论:门诊抗菌药物的应用大体上是合理的,但也存在联用不合理、疗程长、对老年人和小孩用药缺乏相应的调整等问题,有待改善。

OBJECTIVE: To guide rational use of antimicrobials in clinic. METHODS: 11 522 prescriptions, written out between March 1999 and May 1999, were randomly sampled from OPD of our hospital, then the antimicrobials used were analysed in respect to the kinds of drugs, frequency of use, routes of administration and combined use of drugs. RESULTS:There were 58 kinds of antimicrobial used, which accounted for 39. 11% of all drugs used in OPD. Penicillins, quinolones and aminoglycosides were the most common drugs used in OPD. Most of antimicrobials were used alone (75. 30%), 21. 85% of the drugs were used in combination with another and 0. 84% of the drugs were used in manner of four antimicrobial combination. Most drugs were orally given. The longest therapeutic course reached 60 days. CONCLUSION: The use of antimicrobials in the OPD of our hospital was rational on the whole, however, there exist some problems, such as irrationally combined use, long therapeutic course and lack of appropriate adjustment in treatment for old people and children. Clinical doctors should pay attention to these problems.