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莫诺美地治疗冠心病心绞痛35例临床观察

Clinical Observation of Coronary Heart Disease with Angina Pectoris Treated with Mono Mack
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摘要 35例心绞痛患者每日口服莫诺美地25mg,观察心绞痛、胸闷发作次数,心电图变化及其不良反应,结果发现治疗后心绞痛、胸闷发作次数减少(P<0.01),硝酸甘油口含量下降(P<0.01),心电图ST↓(mm)、T倒置导联数,T倒置深度(mm)、T双相导联数及T低平导联数均有改善(P<0.05)。药物不良反应发生率少,提示应用莫诺美地25mg治疗心绞痛有效、安全。 35 patients with AP were treated with Mono Mack capsule 25mg, po, qd for 4 weeks, to study the effect of Mono Mack on angina pectoris caused by CHD. The results showed that the severity and frequency of AP and consumption of ni-troglycerin were reduced (P<0. 01) , and the epression of ST of ECG was improved (P<0. 05). Mono Mack's side effects were mild and reversible. It is suggested that Mono Mack is an effective and safe drug for AP.
出处 《江苏药学与临床研究》 2000年第1期23-25,共3页 Jiangsu Pharmacertical and Clinical Research
关键词 冠心病 心绞痛 5-单硝酸异山梨醇酯 缓解制剂 药物不良反应 莫诺美地 Coronary heart aisease Angina pectoris Isosorbide-S-nitrate
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参考文献3

  • 1Nomenclature and Criteria for Diagnosis of Ischemic Heart Disease.Report of the Joint International Society and Federation of Cardiology World Health Organization Task Force. on standardization of clinical Nomenclature circulation, 1979: 59 : 607.
  • 2王肖龙,王伊清,陈万春.莫诺美地治疗冠心病心绞痛疗效分析[J].国外医学(心血管疾病分册),1997,24(1):36-37. 被引量:4
  • 3骆文香 张银娣 沈连平等.5—硝酸异山梨醇酯缓释剂在健康志愿者体内的药物动力学和生物利用度研究[J].中国药理学会通讯,1997,14(3):23-23.

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