女性系统性红斑狼疮患者血清中催乳素水平的研究

Study on Prolactin in Serum of Female Patients with Systemic Lupus Erythmatosus

用放免法检测了２４名系统性红斑狼疮（ＳＬＥ）妇女及２０名健康对照组血清中催乳素（ＰＲＬ）水平， ＳＬＥ者同时检测ＩｇＧ和ＩｇＭ，结果发现ＳＬＥ伴有高催乳素血症，并且高水平 ＰＲＬ与 ＩｇＧ和 ＩｇＭ呈正相关．提示 ＰＲＬ通过刺激免疫球蛋白的产生诱导 ＳＬＥ发病．

Prolactin was determined from serum of 24 female patients with systemic lupus erythmatosus(SLE) and 20 controls by radioimmunoassay and IgG and IgM of SLE were detected. The results have shown that SLE is with hyperprolactinemia and high PRL has positive relation with IgG and IgM. The results suggest that PRL induces pathogenesis of SLE through stimulating immunoglobulin production.