相转移催化合成邻甲基烯丙氧基酚

The Synthesis of Mathallyloxyphenol Using Phase Transfer Catalyst

在农药呋喃丹的中间体──呋喃酚的合成过程中，邻甲基烯丙氧基酚的合成是较关键的步骤，通常这一步存在选择性差、收率低的缺陷．本文采用相转移催化法进行这一步的反应，邻甲基烯丙氧基酚收率达７０％，

2-Mathallyloxyphenol is a known intermediate for the synthesis of benzofuranol. It can undergo a Claisen rearrangement and subsequent ring closure in a known manner to form benzofran, a precursor to synthesis carbofuran . But its selectivity and yield are usually very low. A new synthesis method employing a phase transfer catalyst is proposed and the overall yield of 70% 2-mathallyloxyphenol based on catalyst is obtained.