早产相关因素323例临床分析

Clinical factors associated with preterm birth: analysis of 323 cases

目的 分析与人工早产和自然早产有关的危险因素。方法 我院1993年1月～1999年12月间分娩的自然早产274例和人工早产49例,分别与同期分娩的足月对照组323例相比,进行早产的因素分析。结果 孕期母亲未作产前检查、胎膜早破、多胎、产前出血、中重度妊高征、内科合并症等均与早产有关;人工早产者产前检查率最低,剖宫产率最高,并主要与产前出血、中重度妊高征、多胎有关;自然早产者产前检查率低于足月对照组,其主要与胎膜早破、不明原因早产有关。结论 孕期多种因素与早产有关,且自然早产和人工早产具有不同的危险因素。

Objective: Our purpose was to evaluate risk factor associations with indicated preterm birth and spontaneous preterm birth. Methods: 323 preterm births delivered in our hospital from Jan. 1993 to Dec. 1999, including 274 spontaneous pretenn births and 49 indicated preterni births, spontaneous preterm births and indicated preterm births were compared with term births respectively to analyze the risk factors of preterni birth. Results: Factors associated with pretemi birth include no antenatal attendance, preterni rupture of membranes, multiple pregnancy, antepartum haemorrhage, preeclampsia. medical disorders, and felaJ malformation. Indicated preterm birth has the lowest rate of antenatal attendance and the highest rate of cesarean section, mostly associated with antepartum haemorrhage, preeclampsia, and multiple pregnancy. The rate of antenatal attendance in spontaneous preterm births was lower than term birth, and was mostly associated with preterm rupture of membranes and idiopalhic preterm birth. Conclusions: There were many clinical factors associated with preterm birth, and indicated preterm birth and spontaneous preterm births have different risk factors.