双歧杆菌耗尽培养上清对菌群失调小鼠肠道菌群的影响

Effect of bifidbacterium SCS on microflora of Mice with Dysbacteriosis

[目的]双歧杆菌(Bifidobacterium)耗尽培养上清(SCS)对菌群失调小鼠肠道生理菌群的影响.[方法]首先腹腔注射青霉素液造菌群失调动物模型,然后分别以双歧杆菌菌液、耗尽培养上清液对菌群失调小鼠进行灌胃治疗.[结果]Bif组、SCS组同自然恢复组的肠道生理菌群相比均有显著性差异.[结论]双歧杆菌SCS对小鼠肠道菌群失调的恢复具有调整作用,尤其对双歧杆菌及乳杆菌有更明显的扶持作用.

[Objective] To evaluate the effect of spent culture supernatant (SCS) of Bifidobacterium on microflora of mice with dysbacteriosis. [Methods] The model of animals with dysbcteriosis was made by means of injecting penicillin into mice adoment, and they were given a therepy of microecology. [Results] There is obvious difference between the normal group and the group of bifidobacterium, and the group of SCS of bifidobacterium. [Conclusions] SCS of bifidobacterium has effect on microflora of mice, which may regulate mice normal physiology functions. It is more obviously helpful to raising bifidobacterium and lactobacillus.