摘要
[目的]研究黄芪成分F3新制剂的急性毒性和最大耐受量.[方法]采用小鼠急性毒性试验方法和最大耐受量测定方法.[结果]小鼠腹腔注射黄芪成分F3新制剂的半数致死量(LD50)未测出,其最小耐受量为5g/kg体重.[结论]黄芪成分F3新制剂是一种毒性作用较小的、有一定开发应用前景的药物.
[Object] Studying acute toxicity and maximum tolerable dose of Astragalus composition F3 new preparation. [Methods] Testing acute toxicity and measuring maximum tolerable dose in mice. [Results] Median lethal dose of Astragalus composition F3 new preparation ip to mice had no result, and the drug's maximum tolerable dose was 5 g/kg. [Conclusion] Astragalus composition F3 new preparation is a drug with relatively poor toxicity and good prospects in exploited and applied fields.
出处
《大连大学学报》
2002年第6期88-89,共2页
Journal of Dalian University
基金
2000年大连市科技计划项目资助
关键词
黄芪
急性毒性
最大耐受量
中国
中药
Astragalus composition F3 new preparation
acute toxicity
maximum tolerable dose
