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端粒酶与内分泌腺肿瘤的关系研究进展

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摘要 端粒酶活性在各种恶性肿瘤及肿瘤衍生的细胞株显著上调,而且与肿瘤细胞的增殖、分化密切相关。端粒酶活性及其催化亚基的检测有助于鉴别诊断内分泌腺良、恶性肿瘤,如甲状腺、肾上腺及卵巢的肿瘤,尤其两者的定量检查更具良好前景。端粒酶活性检测可能较病理检查更能判断肾上腺癌的预后,对卵巢肿瘤的诊断及治疗的指导价值很大。
作者 龚维坤 梁华
出处 《国外医学(内分泌学分册)》 2003年第6期428-431,共4页 Foreign Medical Sciences(Section of Endocrinology)
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