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宫内移植造血干细胞治疗

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摘要 宫内移植造血干细胞(IUHSCT)是替代出生后骨髓移植治疗先天性血液疾病的一种方法。其理论依据是胎儿耐受概念和供者干细胞竞争宿主造血位点。目前,动物实验支持IUHSCT,但临床成功例数不多。通过加强干细胞生物学及移植耐受方面的研究,IUHSCT有可能常规应用于临床。
作者 李东至 何平
机构地区 广州市妇婴医院
出处 《国外医学(计划生育分册)》 2003年第4期217-220,共4页
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  • 1Shields LE, Gaur LK, Cough M,et al. In utero hematopoietic stem cell transplantation in nonhuman primates: the role of T cells.Stem Cells.2003,21:304-314.
  • 2Wilpshaar J, Kanhai HH, Scherjon S,et al.Fetal hematopoiesis during first and second trimester of pregnancy: relevance for in utero stem cell transplantation. Ernst Schering Res Found Workshop,2001,33:173-186.
  • 3Pahal GS, Jauniaux E, Kinnon C,et al.Normal development of human fetal hematopoiesis between eight and seventeen weeks" gestation. Am J Obstet Gynecol,2000,183:1029-1034.
  • 4Donahue J,Carrier E.Non-myeloablative transplants for congenital diseases.Cancer Treat Res,2002,110:177-211.
  • 5Pschera H.Stem cell therapy in utero. J Perinat Med,2000,28:346-354.
  • 6Fujiki Y, Fukawa K, Kameyama K,et al. Successful multilineage engraftment of human cord blood cells in pigs after in utero transplantation.Transplantation,2003,75:916-922.
  • 7Weinberg KI, Kapoor N, Shah AJ,et al.Hematopoietic stem cell transplantation for severe combined immune deficiency. Curt Allergy Asthma Rep,2001,1:416-420.
  • 8Archer DR,Turner CW,Yeager AM,et al.Sustained multilineage engraftment of allogeneie hematopoietie stem cells in NOD/SCID mice after in utero transplantation. Blood,1997,90:3222-3229.
  • 9Flake AW, Zanjani ED.In utero hematopoietic stem cell transplantation: ontogenie opportunities and biologic barriers. Blood,1999,94:2179-2191.
  • 10Bielorai B, Golan H, Rechavi G,et al.Stem-cell transplantation for primary immunodeficiencies.Isr Med Assoc J,2002,4:648-652.

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