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心钠素在心肌病中浓度变化的意义 被引量:3

CHANGES OF CONCENTRATION OF PLASMA ATRIAL NATRIURETIC FACTOR IN PATIENTS WITH CARDIOMYOPATHY
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摘要 本文研究了19例心肌病的血浆心钠素浓度变化,并与风心病及正常人进行了比较。结果显示扩张性心肌病心功能不全组显著高于对照组(P<0.01),且与左房内径和左室舒张末期内径成正相关。作者认为在病程中测定血浆心钠素水平可以作为判断心肌损害程度及病情进展,以及作为估价扩张性心肌病发生心功能不全时的一种非创伤性参数。 The plasma level of atrial natriuretic factor (ANF) in 19 patients with cardiomyopathy was investigated and compared with that of patients with rheumatic heart disease as well as normal volunteers. The results showed that the plasma level of ANF was significantly higher in dilated cardiomyopthy patients than in normal volunteers (P<0.01), and had a positive correlation with left atrial diammer and left ventricular diastolic end diammer. We suggest that early and serial determination of plasma level of ANF may be used as a non-invasive parameter to assess the degree of left ventricular impairment, effect of treatment and patient's prognosis in dilated cardiomyopathy.
出处 《上海医学》 CAS CSCD 北大核心 1992年第4期201-204,共4页 Shanghai Medical Journal
关键词 心钠素 扩张性 心肌病 左房内径 Atrial natriuretic factor Dilated cardiomyopathy Rheumatic heart disease
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  • 1M. Cantin,G. Thibault,H. Haile-Meskel,M. Ballak,R. Garcia,G. Jasmin,J. Genest. Immuno-electron microscopy of atrial natriuretic factor secretory pathways in atria and ventricles of control and cardiomyopathic hamsters with heart failure[J] 1990,Cell and Tissue Research(2):313~322
  • 2Michihisa Jougasaki,Hirofumi Yasue,Ken Okumura,Masashi Mukoyama,Yoshihiko Saito,Kazuwa Nakao,Kiyoshi Takahashi. Atrial natriuretic peptide in the ventricles of patients with dilated cardiomyopathy and human foetuses[J] 1989,The Histochemical Journal(12):715~720

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