喉癌新喉再造术手术切缘的临床病理学研究

TUMOR CLEARANCE AT RESECTION MARGINS FOR LARYNGEAL CARCINOMA: A CLINICOPATHOLOGICAL STUDY

对46例新喉再造术手术标本进行了手术切缘的研究。分别测量标本各方位切缘的距离,并随访全部病例五年以上。切缘阳性者8例(17.4％)。切缘阳性与肿瘤原发部位、肿瘤T分期及肿瘤生长方式相关。切缘阳性病例肿瘤复发或转移率高于切缘阴性病例;切缘距离>5mm者,肿瘤复发或转移率低于切缘距离<5mm者。

Forty-six specimens from resection and reconstruction of larynx for carcinoma were studied. Each part of resection margins was examined and measured the distance beyond tumor, and follow-up was available in all the cases. Presence of tumor at the resection margins was found in 8(17.4%) of the specimens. Positive for tumor at margins was found yte be rela ted to tumor locatian, tumor cla ssification and the growth pattern of tumor. Patients with positive margins were likely to have higher local recurrence or lumph node metastasis than the patients with negative margins (75% vs 13.2%). Patients with resection margin more than 5mm from visible tumor is likely to have a lower loval recurrence or lymph node metastasis.