被动化疗在维持和巩固血吸虫病防治效果中的作用

THE ROLE OF PASSIVE CHEMOTHERAPY IN SCHISTOSOMIASIS CONTROL DURING MAINTAIN AND CONSOLIDATE STAGE

目的 探讨被动化疗在巩固血吸虫病化疗成效和维持低度流行中的作用。 方法 在鄱阳湖原重疫区饭湖和远羊两村分别实施被动化疗结合健康教育 (策略A)和单纯主动全民化疗 (策略B) ,比较两种策略的效果与成本。 结果 1999和 2 0 0 0年粪检阳性者的受治率 ,策略A分别为 96.15 % (5 0 /5 2 )和 97.0 6% (3 3 /3 4) ,策略B均为 10 0 % (4 0 /4 0 ,2 3 /2 3 )。 2年防治的总费用 ,策略A比策略B分别低 49.0 4%和 5 4.60 %。 结论 策略A具有控制效果好、成本低、易被群众接受等优点 ,可替代策略B作为维持和巩固血吸虫病防治效果的策略。

Objective To explore the role of passive chemotherapy in schistosomiasis control and set up the strategy of schistosomiasis control during maintain and consolidate stage. Methods Two high schistosomiasis endemic villages (Fanhu and Yuanyang) were selected and carried out strategy A (passive chemotherapy plus health education) and strategy B (mass chemotherapy only) respectively to compare the cost-effectiveness. Results In strategy A the treatment rate of positive population was 96.15%(50/52) and 97.06%(33/34) respectively in 1999 and 2000, and in strategy B the rate was 100%(40/40) and 100%(23/23). But the total cost of strategy A was 49.04% and 54.60% lower than strategy B respectively. Conclusion Strategy A possess of some advantages, low cost, efficacy and acceptable for residents. It can be used as the strategy of schistosomiasis control during maintain and consolidate stage.