摘要
目的 检测卵巢良性及恶性肿瘤患者血清TPS和CA12 5水平及卵巢癌患者两疗程化疗前后二者水平的变化。为卵巢癌的临床诊断、病情监测提供新方法。方法 用ELISA法分别检测血清TPS和CA12 5水平。结果 卵巢癌患者血清TPS和CA12 5水平均较良性肿瘤患者高 ,差异有显著性。血清TPS和CA12 5诊断卵巢癌的敏感度和特异度无差别。卵巢癌患者两疗程化疗后血清TPS和CA12 5水平显著下降。结论 血清TPS和CA12 5均可作为卵巢癌诊断、病情监测的临床指标 ,二者联合检测可提高其临床应用价值。
objective We have measured the serum levels of TPS and CA125 in patients with ovarian neoplasm and the variation of them before and after chemotherapy in patients treated as ovarian cancer,in order to determine their clinical significance in diagnosis and monitoring of ovarian cancer.Methods Serum levels of TPS and CA125 are both detected by means of ELISA.Results Both serum TPS and CA125 levels in carcinoma patients are significantly higher than that in benign patients.Serum TPS and CA125 show similar sensitivities and specificities in diagnosis of ovarian cancer and their levels both decreased significantly after 2 course of chemotherapy.Conclusions Serum TPS and CA125 are both useful in the diagnosis and monitoring of ovarian cancer,Their clinical value can be increased by combined use of them.
出处
《河南肿瘤学杂志》
2003年第5期326-328,共3页
Henan Journal of Oncology
