重建组织工程化皮肤生物学功能研究

Researching for Reconstructing the Physiological Function of Artificial Skin

皮肤是人体最大的器官 ,易受到内外异常因素的损害而导致各种创伤。组织工程化皮肤为促进皮肤创伤修复起了很大的作用 ,但由于组织工程化皮肤只具备生理皮肤的相似结构 ,不具备其正常生物学功能 ,不能实现患者对皮肤创伤实现“完美愈合”的理想 ,难以广泛应用于临床。因此 ,构建具有生物学功能的理想人工皮肤是皮肤组织工程研究的重要课题。总结了当前组织工程化皮肤的缺陷 ,提出构建具有生物学功能人工皮肤的策略。

Skin is the bigest organ that is easy to be injured by varies of environmental factors.Tissue engineered skin has made great progress in repairing skin scars.It's application was limited by absence of the biological function of human skin.It is a important objective to reconstruct the physiological function of artificial skin in vitro.The deficiency of artificial skin and the strategy of reconstructing an ideal artificial skin was reviewed and proposed.;