急性胰腺炎肝脏损伤的表现及其发病机制的研究进展

Liver injury in acute pancreatitis and its pathogenesis

急性胰腺炎常累及肝、肺及肾脏等远处器官,尽管急性胰腺炎时肝脏损伤多较轻,但对终末期肝功能衰竭目前尚无 好的治疗方法。本文综述了急性胰腺炎肝脏损伤的表现及发病机制,旨在进一步理解急性胰腺炎时全身炎症反应和多器官衰 竭的机制,为探索其防治措施提供新的思路。

Acute pancreatitis is a multiple system disease with alternations not only in the pancreas, but also in the distant organs such as the liver, lung and kidney, etc. Although liver injury is usually slight in acute pancreatitis, there is no better therapy for the end-stage hepatic 'failure. Liver injury and its pathogenesis in acute pancreatitis was reviewed to further understand the mechanisms of systemic inflammatory response and multiple organ failure, and to supply a new way for the prevention and treatment of acute pancreatitis.