摘要
综述了α-蒎烯通过KMnO4氧化和臭氧化合成蒎酮酸,以及由蒎酮酸合成四元环类衍生物的研究现状。KMnO4氧化法有常规氧化、相转移催化和表面活性剂催化3种方法。由蒎酮酸合成的四元环类化合物主要包括具生理活性的化合物、性信息素、与药物和氨基酸合成有关的化合物、保幼激素类似物、蒎酸型化合物及其他化合物。同时,提出加强β-蒎烯合成四元环类化合物的建议。
Synthesis of pionic acid from α-pinene by permanganate oxidation or ozonolysis, and synthesis of cyclobutane ring derivatives of pinonic acid have been reviewed. Permanganate oxidation can be classified into three methods, namely normal oxidation, phase transfer catalysis and surfactant catalysis. The cyclobutane ring compounds include bio-activity compounds, compounds related to medicine and amino-acid, sex pheromone, juvenile hormone analogs, pinic acid type compounds and so on. It is proposed that more study on synthesis and application of cyclobutane ring compounds should be proceeded. Utilization of β-pinene, which is structurally similar to –pinene and abundant in China, to synthesis cyclobutane ring compounds is also proposed.
出处
《江西农业大学学报》
CAS
CSCD
2003年第5期789-793,共5页
Acta Agriculturae Universitatis Jiangxiensis
基金
江西省自然科学基金资助项目(982019)
关键词
蒎酮酸
四元环类衍生物
合成
分析
臭氧化
松节油
α-pinene
permanganate oxidation
ozonolysis
pinonic acid
cyclobutane ring compounds
