115例乳腺癌临床分析

Clinical analysis of 115 cases with breast cancer

目的 :总结乳腺癌的发病规律、早期临床表现 ,提高乳腺癌的诊断及治疗水平。 方法 :对 115例乳腺癌患者的临床表现、诊断、治疗和预后进行回顾性分析。 结果 :红外线诊断占 78 3% (18/ 2 3) ,X线钼靶的诊断占93 5 % (2 9/ 31) ,细胞学诊断占 80 % (16 / 2 0 )。分期早期与晚期的雌激素受体 (ER)及抗凋亡相关基因 (Bag 1)的表达差异无统计学意义 (P >0 .0 5 ) ,腋淋巴结转移组与无淋巴结转移组Bag 1的表达差异有统计学意义 (P <0 .0 5 )。随访 89例 ,2年、5年生存率分别为 92 .1% (82 / 89)和 85 7% (5 4 / 6 3)。 结论 :本组乳腺癌患病年龄以 4 1～6 0岁年龄多见 ,红外线、X线钼靶、细胞学检查是诊断乳腺癌的主要手段。早诊断、早治疗是提高乳腺癌患者生存率的关键。

Objective: To study the diagnosis and treatment of breast cancer. Methods: 115 cases with breast cancer were reviewed for their diagnosis, treatment and prognosis. Results: 18 cases were diagnosised by infrared transillumination, 29 cases by mammography and 16 by cytology. The expressions of ER and Bag 1 have no difference between early stage and invasive breast cancer (P>0.05). There is an overexpression of Bag 1 in cases with lymph node metastasis (P<0.05). Eighty nine (77.4%) cases underwent radical operation, sixteen (13.9%) cases underwent modified radical operation and other procedures for 10(8.7%) cases. 89 cases have been followed up: two year and five year survival rates were 82/89(92.1%) and 54/63(85.7%) respectively. Conclusions: Infrared transillumination, mammography and cytological pathology are important means in diagnosis of breast cancer. Early diagnosis and treatment are very important to improve the survival rate of breast cancer patients.